Rescue teams are working on the last overturned car, said Rajesh Modak, deputy inspector general of police in Kanpur. The other cars have been cleared of people, Modak said, according to CNN.
More than 150 passengers have been injured, over 40 of them are seriously injured, Rahul Srivastav, press officer for the Uttar Pradesh police, told CNN.
Kanpur, in Uttar Pradesh state, is nearly 300 miles southeast of New Delhi, the capital.
Rescue operations are going on as volunteers and railway police work to pull passengers trapped in the coaches. The medical team was also rushed to the site to provide first-aid to the victims while those seriously injured were taken to hospitals in Kanpur, as NDTV reports.
Indian Prime Minister Narendra Modi expressed grief over the deaths in the train accident.
“Anguished beyond words on the loss of lives due to the derailing of the Patna-Indore Express. My thoughts are with the bereaved families,” the Prime Minister tweeted.
Indian Railways Minister Suresh Prabhu tweeted that he had ordered an inquiry and “strictest possible action will be taken against those who could be responsible.”
Top railway officials said a fault in the tracks may have caused the accident, which, they said, was the worst they had seen in a long time.